1, chronic granulocytic leukemia (CML) is effective, and can be used for CML resistant to Maryland; 2, on melanoma, renal cancer, head and neck cancer has a certain degree of efficacy, and the combination of radiotherapy on the head and neck and cervical squamous carcinoma is effective.

Adverse reactions

1, myelosuppression is a dose-limiting toxicity, which can lead to leukopenia and thrombocytopenia, and can be recovered in 1-2 weeks after stopping the drug; 2, sometimes gastrointestinal reactions, and there have been reports of testicular atrophy and teratocarcinoma; 3, there are occasional symptoms of central nervous system and alopecia, and there have been reports of drug-induced fevers, which can reappear with repeated administration of the drug.