Doctor, what kinds of growth hormone are there? What are the differences? "

"Doctor, is powder or water suitable for growth hormone in children?"

"Doctor, which brand of growth hormone water is good?"

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In real life, there are a lot of parents worried about their children's height, even if they bypassed all the misunderstandings, and it was hard to find the right way to get to the doctor, but when it comes to the need to use growth hormone, it's full of doubts, and the face of the choice of medicines is infinitely entangled. How to choose a growth hormone? Which dosage form is better for your child? Which growth hormone is more effective? Today, the evaluation team will be divided into several ways, in response to the parents' confusion, invited a number of tertiary hospitals in the field of child growth and development of well-known experts, from the perspective of the parents are most concerned about the issue of the market growth hormone brands on the product information to explain in detail, I hope to give a little help to the confused parents.

The first thing you need to know is to know each other, and this is true for everything, and growth hormones are no exception. So, let's start by counting the major brands of growth hormones that are currently available in China, so that we can have a good idea of what we're talking about.

Domestic major growth hormone products comprehensive information list

The above chart just shows a general overview of the major domestic growth hormone products, specifically back to how to choose a suitable growth hormone for children? Don't worry, let's look at it step by step.

Faced with a multitude of growth hormone brands and products, many first-time parents and friends are confused. How do you learn to simplify and understand the difference between the many pieces of information out there? Listen to what the experts have to say.

Medical Doctor, Professor/BoD, Peking Union Medical College? Dr. Xueyan Wu, Chief Physician, Department of Endocrinology, Peking Union Medical College Hospital

Q: What kinds of growth hormone are there? What is the difference?

A: According to the form of growth hormone preparations can be divided into lyophilized powder injection and liquid aqueous injection. Natural growth hormone originally exists in liquid form in body fluids. Initially, in order to solve the problem of long-term storage of growth hormone, and at the same time by the early formulation technology limitations, it can only be low-temperature dehydration made of lyophilized powder injection, just like the invention of the refrigerator before the people generally only the fresh meat cured air-dried bacon, in order to achieve the purpose of long-term preservation of the non-degradation of the same; the other preparation, the more physiological and natural form of the liquid form of the existence of the aqueous injection type. Compared with lyophilized powder injections, aqueous injections have a molecular structure closer to natural, higher purity and activity, fewer antibodies, and are more convenient to use. Obviously, the latter is the result and product of advances in formulation technology.

In addition, according to the duration of action, growth hormone can be divided into short-acting and long-acting preparations. Short-acting contains lyophilized powder injection and short-acting aqueous injection; long-acting preparation is long-acting growth hormone aqueous injection, which is the revolutionary progress of protein-based biological preparation technology in the history of human pharmaceuticals! At present, a large number of clinical application experience has proved that the long-acting growth hormone aqueous injection preparation and short-acting aqueous injection preparation are as safe and effective as each other. Apart from the differences in molecular structure and combination, the biggest difference between short-acting and long-acting preparations is whether they need to be injected every day. Short-acting formulations require daily injections, 365 injections a year. Long-acting, on the other hand, can be extended to once a week, requiring only 52 injections a year. As a result, patients using the long-acting formulations, especially those who fear frequent injections, students who live in schools and only have the opportunity to go home on weekends, and adults who travel frequently, have a much higher level of adherence to treatment and convenience, as well as a much greater degree of privacy.

In order to provide parents with a clearer and more intuitive understanding, we have summarized the growth hormone brands on the market by dosage form in the chart below.

Growth hormone product dosage form brand related information comparison chart

Knock on the blackboard: growth hormone can be divided into powder, short-acting aqueous and long-acting aqueous; aqueous is closer to the natural growth hormone than powder, purity and activity is higher, fewer antibodies, and more convenient to use; long-acting growth hormone is lower than the short-acting frequency of injection, weekly injections instead of daily injections, calculated to reduce 313 injections per year, and the number of children is reduced. It is less frequent than short-acting injections, with weekly injections replacing daily injections, which is calculated to be 313 fewer injections per year, making it easier for children to accept; the launch of LLGH represents a revolutionary advancement in protein-based biologics.