In 1930, the Department of Health promulgated quarantine regulations, and the Customs Supervision and Consular Corps in the main seaport of Shanghai were responsible for declaring epidemic areas.

Quoted from the "Old Customs General Order Database for Publishing Modern Chinese Historical Materials Database" General Customs and Taxation Department General Order No. 4304 (Second Series) "Reviewing the Development of China's Quarantine Affairs and its Relationship with the Customs" on September 9, 1931 Transfer quarantine and port health matters that belong to the rights of sovereign states to the Seaport Quarantine Department of the Ministry of Health"