According to the information you provided, if your annual salary is 6.5438+0.5 million yuan and you have worked in Chengdu for 654.38+00 years, you'd better buy a house of about 80 square meters. The price of houses in this area is usually around 20 thousand, so the total price is about 1.6 thousand. If you plan to purchase by loan, it is suggested that the monthly payment should not exceed 30% of your income, and you can choose a loan with a monthly payment of about 4,500 yuan.

Please note that this is only a general suggestion, and the actual purchase decision may need to be adjusted according to your personal situation and market conditions. In addition, please be sure to consult a professional real estate lawyer or real estate agent before buying a house to understand the relevant laws and policies.