RMB 50,000 is a fixed deposit. A fixed deposit is a deposit kept in the bank for a certain period of time.

The unit is yuan and cents. The monthly interest rate refers to the ratio of the interest receivable by the bank to the fixed deposit. The monthly interest rate is generally expressed in thousandths. The monthly interest rate of 3.75 means 3.75 per thousand, which is expressed as a percentage of 0.375%. The calculation of this regulation is as follows: 50000*0.375%=187.5 yuan. Answer: The monthly interest of 50,000 yuan with a monthly interest rate of 3.75 is 187.5 yuan.