Biomedical engineering is a new comprehensive subject. It is a new subject field formed by the interweaving of modern engineering science, physical science and life science. From 65438 to 0979, Professor Van C. Mow, the national scientific adviser and director of the Biomechanics Laboratory of Rensselaer Institute of Multidisciplinary Engineering, led the first American biomedical engineering delegation to China. Through academic exchanges and visits, it has played a certain role in the development of biomedical engineering in Beijing, Guangzhou and Chengdu. The following year, Kang was invited to attend Gordon's symposium on bioengineering and orthopedics in the United States, which broadened his horizons, obtained the latest information on biomedical engineering, and sprouted a strong desire to apply modern engineering science and physical science to solve medical and biological problems.
Kang and Wu, a medical professor at West China University of Medical Sciences, jointly advocated and promoted the research of biomedical engineering and biomechanics. Faced with the difficulties of no money, no people and no equipment, he and several teachers began their research work sleepless nights.
On the one hand, he ran around to win the support of Sichuan Science and Technology Commission, Chengdu University of Science and Technology and other relevant departments for this emerging discipline, and invited science and engineering and medical workers from relevant universities to make suggestions and suggestions for the development of this discipline; On the other hand, he devoted himself to the study of biomechanics.
From 1979, in less than 10 years, under the leadership of Kang, Chengdu University of Technology established a large biomechanics laboratory, trained a scientific research team with high academic level, and opened research topics such as biofluid mechanics, biosolid mechanics, sports biomechanics and biological information and control, forming cardiovascular hemodynamics, biomechanics of cardiovascular bones, soft tissues and teeth and clinical applications; Information, control and data processing of biological system and mechanical simulation system have undertaken 15 national and provincial key research projects, completed a number of influential scientific papers and achievements at home and abroad, and read papers 15 times at international academic conferences. Many emerging branches of biomedical engineering, such as medical polymer materials, medical pyrolytic carbon materials and artificial organs, have developed rapidly in Chengdu University of Science and Technology, and established long-term and stable cooperative relations with West China University of Medical Sciences and other units. Kang and Wu, together, extensively contacted universities and research institutes in Sichuan Province, organized and established the Sichuan Biomedical Engineering Society, founded the magazine Biomedical Engineering, and established the Sichuan Biomedical Engineering R&D Center in conjunction with relevant enterprises. Because of Kang's creative research work in the field of biomechanics and his popularization in the field of biomechanics in China, he has become one of the recognized academic leaders of biomechanics in China. 1983 was appointed as the first chairman of Biomechanics Committee of theoretical and applied mechanics Institution in China, 1985 was elected as the second executive director of China Biomedical Engineering Society, and served as the deputy editor of China Journal of Biomedical Engineering. He was the head of the China delegation to the 2nd China-Japan-US Biomechanics International Conference 1985 and the Chinese chairman to the 3rd China-Japan-US Biomechanics International Conference199. /kloc-0 was admitted as a member of the European Biomechanics Society in April, 1985, and was specially invited to attend the 5th European Biomechanics Congress held in September, 1986 in the Federal Republic of Germany, where he gave a report and served as the executive chairman. He gave a report on cardiovascular fluid dynamics at this conference, and put forward the concept and content of the discipline of heart valve fluid dynamics for the first time, which attracted the attention of the European biomechanics community. 1In April, 986, Chinese-American professors wrote to Kang twice, informing him that as an outstanding biomechanical scholar, he was elected as a member of the steering committee of the World Biomechanics Congress.
As Yang Guitong, the current director of the Biomechanics Professional Committee, wrote in the preface of the Proceedings of the Third National Biomechanics Academic Conference: "The development of biomechanics in China should also thank Mr. Kang for his outstanding contribution. He successfully led the first Biomechanics Committee. Under his leadership, the work of the Biomechanics Professional Committee has developed vigorously, which has played a very good role in the academic circles at home and abroad and had a great influence, making China have its own place in some international biomechanics disciplines. This is well known.
Hydrodynamic study of heart valve opening
Development of artificial heart valve
There are four subtle components in the human heart-heart valve, which is a "valve" that only allows blood to flow forward and prevents blood from flowing backward, so that the heart plays the role of blood pump in the cardiovascular system. But when they are diseased for some reason, it will affect the function and efficiency of the whole heart and form valvular heart disease. Millions of people in the world suffer from this disease every year, so it is of great clinical and scientific significance to study the mechanical characteristics and movement law of heart valves, especially in the last twenty or thirty years, the advent of artificial heart valves has played a great role in saving the lives of patients with severe heart valve diseases. Therefore, the research on the fluid dynamics of artificial heart valve has become an extremely active research field in the fluid dynamics of heart valve.
From 65438 to 0979, when Kang and his colleagues just started to March into biomechanics, they decided to take the hemodynamics of cardiovascular system, especially the hemodynamics of heart valves, as their main research direction.
The research on the mechanism of natural closure of heart valves began in the late 1970s. Some biomechanics and physiologists in the world have put forward six or seven theories, such as eddy current theory and reverse pressure gradient theory, which are still controversial at present, and none of them can fully explain the whole process of heart valve closing movement. Kang Huang Zhen believes that a single factor cannot play a role in the mechanism of heart valve closure. After research, he and his assistants put forward a new comprehensive factor theory, which is in good agreement with the simulation results and the effective areas of the above two theories. 65438-0984, this work has attracted the attention of scholars at home and abroad at the international symposium on frontier issues of applied mechanics and biomechanics.
In the aspect of design theory of artificial heart valve, in 1983, Kang and his colleagues put forward a new design theory of mechanical artificial heart valve-bilobed wing valve, pointing out that better hemodynamic characteristics can be obtained by designing mechanical heart valve with wing flow theory. 1In May, 983, at the first international symposium on biomechanics held in Wuhan, China, Japan and the United States, Kang reported the theoretical and experimental results of steady flow and pulsating flow. This report was immediately praised by foreign experts such as Feng Yuanzhen and Van C. Mow. Professor Feng Yuanzhen called it: "This is a beautiful paper ... It is an original academic idea to introduce wing theory into heart valve design." In July of the same year, he was invited to read the paper "Research on the Design Theory of Artificial Heart's White Leaf Mechanical Valve" at the International Symposium on Hemoperfusion and Artificial Organs, and further elaborated this theory, which caused great repercussions. Some foreign experts believe: "Although China started late in this field, it has developed rapidly and is close to the international level."
Around the hydrodynamic research of artificial heart valve, Kang and his assistants also carried out theoretical and experimental research on the simulation of blood circulation system. 1984 put forward the "distributed-subsection centralized three-parameter four-cell model" of blood circulation system and a set of relatively complete design theories and methods, and read out the paper "Design Theory and Application of Pulsating Flow Simulated Blood Circulation System" at the second national annual meeting of biomedical engineering held in Jinan in May 1984. According to this theory, a pulsatile flow simulation device of artificial heart valve and a simulation experiment device of pulmonary circulation system with high simulation degree and excellent performance are developed.
199 1 year, Kang published the first systematic monograph "Fluid Mechanics of Heart Valve", and proposed to establish the system framework of fluid mechanics of heart valve for the first time at home and abroad. In June 5438+10, he went to Warsaw to teach this subject at the invitation of Polish Academy of Sciences.
Kang and his assistants not only devoted themselves to the theoretical study of the fluid dynamics of heart valves, but also carried out the design, development and clinical application of artificial heart valves. According to their own design theory of thin-wing mechanical valve with hinged two leaflets, they joined Chengdu University of Technology and West China University of Medical Sciences to form an interdisciplinary joint research group, and successfully developed a new type of artificial mechanical heart valve with advanced hemodynamic characteristics, which has been used in clinical trials and contributed to the development of independent artificial heart valves in China. At the same time, Kang and his assistants have also made achievements in the hydrodynamic theory and material characteristics of biological heart valves and the development of Sichuan yak pericardial biological heart valves.
Teach knowledge and educate people.
"It is our teachers' bounden duty to train talents for the four modernizations," Kang often said.
Kang has been actively teaching and educating people since he was a child. After the founding of the People's Republic of China, he went to many schools and used his spare time to translate and write a large number of foreign language materials and teaching materials.
1980 after he became the vice president of Chengdu university of science and technology, he still insisted on working in the front line of teaching; At the end of 1983, after serving as the vice governor, he remained as the director of the Institute of Mechanics of Chengdu University of Science and Technology and insisted on guiding graduate students in his spare time. Working in the provincial government during the day, graduate students often ask him for advice at night. He said: "It is very important to take good care of graduate students. China's career has to be inherited by these young people. So I teach them what I know in time, and guide them to learn if I don't know, so that they can grow up quickly. " Kang not only teaches students knowledge and skills, but also pays attention to cultivating students' style of study. He often tells students that there are three most important points in the style of study: first, there must be a down-to-earth spirit; The second is to be creative; The third is to have tough perseverance. Only in this way can we contribute to the cause of science.
In the work of teaching and educating people, he set an example and trained successors with his rigorous and down-to-earth work style and noble party member moral sentiment. He is willing to selflessly dedicate all new ideas and experiences to students and colleagues. Every time he comes back from abroad, he gives all kinds of materials and books to the teaching and research section and laboratory, and never takes them for himself.
Kang has only country and career in mind. After he became the vice governor, the provincial government gave him a house, the usable area was nearly twice as large as that of his school house, and the facilities were much better, but he insisted not to, because it was more convenient to live in the school for scientific research. In life, he is even more simple and thrifty, self-denial and dedication. 1in June, 984, he and an assistant traveled to the United States for three weeks and only spent $54 on living expenses. In order to save foreign exchange for the country, he often lives in student dormitories and eats in small restaurants when giving lectures and visiting abroad. During his several visits, he handed over the surplus public and miscellaneous expenses and living expenses to the state. 199 1 was awarded the title of "Excellent party member" by Sichuan Provincial People's Congress.
Under the influence and leadership of Kang, a group of young and middle-aged teachers and graduate students grew up rapidly. Over the past decade or so, of the more than 20 graduate students he has supervised, two have obtained doctoral degrees, two have studied abroad, and the rest have been working in biomedical engineering or related jobs. Professor Bai Shiyi, a famous scientist, wanted to leave him in the United States in his early years. He said to Kang, "You are right to return to China! The socialist motherland is indeed a vast world of great use. " Kang is over 70 years old. He is currently the deputy director of the Standing Committee of Sichuan Provincial People's Congress and the vice chairman of the Central Committee. For the sake of science and technology education and health in Sichuan province, for the development of biomechanics and biomedical engineering, and for the four modernizations of the motherland, he is still making every effort to continue exploration and keep making progress.