Why do children get allergic rhinitis? I think this is a question that most parents would like to understand. The symptoms of allergic rhinitis and colds have many similarities, and many people mistakenly think that they have a cold and do not care about it, so they delay the condition. Unbeknownst to them, if left untreated, it is likely to cause other illnesses. First of all, let's understand why children suffer from allergic rhinitis.
One, genetic factors. Allergic allergic rhinitis is an abnormal immune response of the body and is the result of many factors. About 80% of children with allergic rhinitis can be found in their relatives have a history of allergic rhinitis, maternal inheritance is more obvious. Allergic rhinitis is inherited in different ways and is the result of genetic mutations and environmental ****similar changes. Current molecular level research shows that allergic rhinitis is controlled by multiple genes, and the symptoms of asthma, rhinitis, and atopic dermatitis vary in degree due to different gene expression. Scholars agree that "airway hyperresponsiveness in certain environments is associated with the occurrence of mutations in the genes of the region". The mutated genes include those related to the regulation of immunoglobulin EIgE serum levels, genes regulating Thl and Th2 cytokines, and genes related to transcription factors, initiation factors, and leukotrienes.
Two, dietary factors. Allergic rhinitis is related to diet, especially in infants and young children. Studies have found that mixed and artificially fed infants and young children are more likely to develop allergic rhinitis than breastfed infants and young children, which means that breastfeeding has a preventive effect on the development of allergic rhinitis in infants and young children before the age of 2 years. Studies have shown that increased intake of vitamins, grains, and starches can lead to a significant reduction in the prevalence and severity of allergic rhinitis, conjunctivitis, and asthma. On the contrary, increased intake of high-fat, high-protein diets can induce the development of allergic diseases, probably because the metabolites of polyvalent unsaturated fatty acids in such foods cause changes in the function of lymphocytes, resulting in an imbalance of Thl and Th2 cytokines and an increase in antibodies to the immunoglobulin EIgE, which promotes both specific and nonspecific immune responses.
Three, environmental factors. Allergic rhinitis prevalence is a global trend of increasing, current research is believed to be the result of environmental factors, the most authoritative theory is the "hygiene hypothesis", the core of which is "modern environmental pollution increases, and the development of children by bacterial and viral infections caused by the reduction of immune response, so that the prevalence of allergic diseases increased The centerpiece of this theory is that "the increase in pollution in the modern environment and the decrease in the immune response to bacterial and viral infections during childhood development have led to a higher prevalence of allergic diseases.